2 Comments
Mar 7Liked by Cassandra Quave

Yikes, and thanks for highlighting this. In terms of efficacy and side effects, a combination of adapalene (name brand Differin) and benzoyl peroxide is considered a good first line treatment combination for mild/moderate acne in primary care guidelines.

The combination is called Epiduo.

From what you're reporting, it seems like temperature control is a very overlooked imperative to help prevent BPO--> benzene break down.

Will read more about this and check back in if there are statements from the medical journals/authorities I follow. For now I'm thinking I'll continue with the salicylic acid and cleansing regimen my wife coordinates with our daughter... and skip the benzoyl peroxide.

Adapalene can cause a temporary worsening of acne and skin irritation, so it's hard to get sustained compliance for many.

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Thanks for sharing this info on the combo with the adapelene. There is a lot of discussion about the news in the dermatology community. I expect we’ll see some commentaries out soon in the derm medical literature this spring.

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