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I find this endlessly fascinating! Thank you for this and the work you do.

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Thanks so much! So glad you enjoyed it :)

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Apr 11Liked by Cassandra Quave

Fascinating, and so interesting that a lot of these compounds were teased out over thousands of years in Chinese medicine. Do you see any role for AI in winnowing down candidate molecules at this time?

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Ohh - this is a great question! I recently saw a talk about a team using generative AI to generate antibiotic structures based on a learning model on structural features of antibiotics and their activities against different bacterial targets. It has shown some promise. I'd love to see how we could use machine learning and maybe even generative AI to optimize SAR on natural products.

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